Fare Guide

Estimated lowest fares found within 7 days

Cheapest Airline Avianca

The cheapest airline(s) flying from Santo Domingo to Santiago is Avianca.

  • Avianca Avianca
Cheapest Month March

Travel Period: January 2025 - December 2025

The cheapest month(s) to fly from Santo Domingo to Santiago is March.

  • Jan 2025
  • Feb 2025
  • Mar 2025
  • Apr 2025
  • May 2025
  • Jun 2025
  • Jul 2025
  • Aug 2025
  • Sep 2025
  • Oct 2025
  • Nov 2025
  • Dec 2025
Cheapest Day of the Week Tuesday

The cheapest day(s) of the week to fly from Santo Domingo to Santiago is Tuesday.

  • Sun Sunday
  • Mon Monday
  • Tue Tuesday
  • Wed Wednesday
  • Thu Thursday
  • Fri Friday
  • Sat Saturday

Flight Schedules

Last Updated: Mon, 2 Dec, 2024

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  • Availability
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  • 06:23 SDQ
    20:20 SCL
    12Hrs, 57m 1 Stop (PTY)
  • SDQSanto Domingo Las Americas Airport 06:23 - SCL 20:20 12h 57m 1 Stop (PTY) Panama City
  • SDQSanto Domingo Las Americas Airport 06:23
    PTYPanama City Tocumen International Airport 11:47
  • PTYPanama City Tocumen International Airport 08:00
    SCLSantiago Arturo Merino Benitez Airport 20:20
  • 12h 57m (3h 47m)
  • 1 Stop PTY · Panama City 3h 47m
  • Copa Airlines (CM 108)Boeing 737 700
    Copa Airlines (CM 395)Boeing 737 Max 9 Passenger
  • Copa Airlines (CM 108)
    • M
    • T
    • -
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    • -
    • -
    • S
  • 06:23 SDQ
    20:20 SCL
    12Hrs, 57m 1 Stop (PTY)
  • SDQSanto Domingo Las Americas Airport 06:23 - SCL 20:20 12h 57m 1 Stop (PTY) Panama City
  • SDQSanto Domingo Las Americas Airport 06:23
    PTYPanama City Tocumen International Airport 11:47
  • PTYPanama City Tocumen International Airport 08:00
    SCLSantiago Arturo Merino Benitez Airport 20:20
  • 12h 57m (3h 47m)
  • 1 Stop PTY · Panama City 3h 47m
  • Copa Airlines (CM 108)Boeing 737 800
    Copa Airlines (CM 395)Boeing 737 Max 9 Passenger
  • Copa Airlines (CM 108)
    • -
    • -
    • W
    • -
    • F
    • S
    • -
  • 08:53 SDQ
    20:20 SCL
    10Hrs, 27m 1 Stop (PTY)
  • SDQSanto Domingo Las Americas Airport 08:53 - SCL 20:20 10h 27m 1 Stop (PTY) Panama City
  • SDQSanto Domingo Las Americas Airport 08:53
    PTYPanama City Tocumen International Airport 11:47
  • PTYPanama City Tocumen International Airport 10:30
    SCLSantiago Arturo Merino Benitez Airport 20:20
  • 10h 27m (1h 17m)
  • 1 Stop PTY · Panama City 1h 17m
  • Copa Airlines (CM 267)Boeing 737 800
    Copa Airlines (CM 395)Boeing 737 Max 9 Passenger
  • Copa Airlines (CM 267)
    • -
    • T
    • -
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    • F
    • S
    • S
  • 08:53 SDQ
    23:47 SCL
    13Hrs, 54m 1 Stop (PTY)
  • SDQSanto Domingo Las Americas Airport 08:53 - SCL 23:47 13h 54m 1 Stop (PTY) Panama City
  • SDQSanto Domingo Las Americas Airport 08:53
    PTYPanama City Tocumen International Airport 15:14
  • PTYPanama City Tocumen International Airport 10:30
    SCLSantiago Arturo Merino Benitez Airport 23:47
  • 13h 54m (4h 44m)
  • 1 Stop PTY · Panama City 4h 44m
  • Copa Airlines (CM 267)Boeing 737 800
    Copa Airlines (CM 497)Boeing 737 800
  • Copa Airlines (CM 267)
    • -
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    • -
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    • S
  • 11:50 SDQ
    23:40 SCL
    10Hrs, 50m 1 Stop (BOG)
  • SDQSanto Domingo Las Americas Airport 11:50 - SCL 23:40 10h 50m 1 Stop (BOG) Bogota
  • SDQSanto Domingo Las Americas Airport 11:50
    BOGBogota Airport 15:30
  • BOGBogota Airport 13:25
    SCLSantiago Arturo Merino Benitez Airport 23:40
  • 10h 50m (2h 05m)
  • 1 Stop BOG · Bogota 2h 05m
  • Avianca (AV 209)Airbus A320 Neo
    Avianca (AV 241)Airbus A320 Neo
  • Avianca (AV 209)
    • M
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    • -
    • -
    • -
    • -
    • -
  • 11:50 SDQ
    23:40 SCL
    10Hrs, 50m 1 Stop (BOG)
  • SDQSanto Domingo Las Americas Airport 11:50 - SCL 23:40 10h 50m 1 Stop (BOG) Bogota
  • SDQSanto Domingo Las Americas Airport 11:50
    BOGBogota Airport 15:30
  • BOGBogota Airport 13:25
    SCLSantiago Arturo Merino Benitez Airport 23:40
  • 10h 50m (2h 05m)
  • 1 Stop BOG · Bogota 2h 05m
  • Avianca (AV 209)Airbus
    Avianca (AV 241)Airbus A320 Neo
  • Avianca (AV 209)
    • -
    • -
    • -
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  • 17:50 MDE
    13:25 BOG
    12Hrs, 50m 1 Stop (SCL)
  • MDEMedellin Jose Maria Cordova Intl Airport 17:50 - BOG 13:25 12h 50m 1 Stop (SCL) Santiago
  • MDEMedellin Jose Maria Cordova Intl Airport 17:50
    SDQSanto Domingo Las Americas Airport 11:50
  • SCLSantiago Arturo Merino Benitez Airport 01:40
    BOGBogota Airport 13:25
  • 12h 50m (3h 19m)
  • 1 Stop SCL · Santiago 3h 19m
  • Avianca (AV 123)Airbus A320 Neo
    Avianca (AV 209)Airbus A320 Neo
  • Avianca (AV 123)
    • M
    • -
    • -
    • -
    • -
    • -
    • -
  • 11:53 SDQ
    03:24 SCL
    14Hrs, 31m 1 Stop (PTY)
  • SDQSanto Domingo Las Americas Airport 11:53 - SCL 03:24 14h 31m 1 Stop (PTY) Panama City
  • SDQSanto Domingo Las Americas Airport 11:53
    PTYPanama City Tocumen International Airport 18:51
  • PTYPanama City Tocumen International Airport 13:30
    SCLSantiago Arturo Merino Benitez Airport 03:24
  • 14h 31m (5h 21m)
  • 1 Stop PTY · Panama City 5h 21m
  • Copa Airlines (CM 129)Boeing 737 Max 9 Passenger
    Copa Airlines (CM 172)Boeing 737 800
  • Copa Airlines (CM 129)
    • -
    • -
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    • -
    • -
    • -
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  • 11:53 SDQ
    00:05 SCL
    11Hrs, 12m 1 Stop (PTY)
  • SDQSanto Domingo Las Americas Airport 11:53 - SCL 00:05 11h 12m 1 Stop (PTY) Panama City
  • SDQSanto Domingo Las Americas Airport 11:53
    PTYPanama City Tocumen International Airport 15:32
  • PTYPanama City Tocumen International Airport 13:30
    SCLSantiago Arturo Merino Benitez Airport 00:05
  • 11h 12m (2h 02m)
  • 1 Stop PTY · Panama City 2h 02m
  • Copa Airlines (CM 129)Boeing 737 800
    Copa Airlines (CM 171)Boeing 737 800
  • Copa Airlines (CM 129)
    • M
    • -
    • -
    • -
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    • -
    • -
  • 11:53 SDQ
    00:05 SCL
    11Hrs, 12m 1 Stop (PTY)
  • SDQSanto Domingo Las Americas Airport 11:53 - SCL 00:05 11h 12m 1 Stop (PTY) Panama City
  • SDQSanto Domingo Las Americas Airport 11:53
    PTYPanama City Tocumen International Airport 15:32
  • PTYPanama City Tocumen International Airport 13:30
    SCLSantiago Arturo Merino Benitez Airport 00:05
  • 11h 12m (2h 02m)
  • 1 Stop PTY · Panama City 2h 02m
  • Copa Airlines (CM 129)Boeing 737 Max 9 Passenger
    Copa Airlines (CM 171)Boeing 737 800
  • Copa Airlines (CM 129)
    • -
    • -
    • -
    • -
    • -
    • S
    • -
  • 11:53 SDQ
    23:47 SCL
    10Hrs, 54m 1 Stop (PTY)
  • SDQSanto Domingo Las Americas Airport 11:53 - SCL 23:47 10h 54m 1 Stop (PTY) Panama City
  • SDQSanto Domingo Las Americas Airport 11:53
    PTYPanama City Tocumen International Airport 15:14
  • PTYPanama City Tocumen International Airport 13:30
    SCLSantiago Arturo Merino Benitez Airport 23:47
  • 10h 54m (1h 44m)
  • 1 Stop PTY · Panama City 1h 44m
  • Copa Airlines (CM 129)Boeing 737 Max 9 Passenger
    Copa Airlines (CM 497)Boeing 737 800
  • Copa Airlines (CM 129)
    • -
    • -
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    • -
    • -
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    • S
  • 11:53 SDQ
    23:47 SCL
    10Hrs, 54m 1 Stop (PTY)
  • SDQSanto Domingo Las Americas Airport 11:53 - SCL 23:47 10h 54m 1 Stop (PTY) Panama City
  • SDQSanto Domingo Las Americas Airport 11:53
    PTYPanama City Tocumen International Airport 15:14
  • PTYPanama City Tocumen International Airport 13:30
    SCLSantiago Arturo Merino Benitez Airport 23:47
  • 10h 54m (1h 44m)
  • 1 Stop PTY · Panama City 1h 44m
  • Copa Airlines (CM 129)Boeing 737 800
    Copa Airlines (CM 497)Boeing 737 800
  • Copa Airlines (CM 129)
    • -
    • T
    • -
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    • -
    • -
  • 11:53 SDQ
    03:47 SCL
    14Hrs, 54m 1 Stop (PTY)
  • SDQSanto Domingo Las Americas Airport 11:53 - SCL 03:47 14h 54m 1 Stop (PTY) Panama City
  • SDQSanto Domingo Las Americas Airport 11:53
    PTYPanama City Tocumen International Airport 19:14
  • PTYPanama City Tocumen International Airport 13:30
    SCLSantiago Arturo Merino Benitez Airport 03:47
  • 14h 54m (5h 44m)
  • 1 Stop PTY · Panama City 5h 44m
  • Copa Airlines (CM 129)Boeing 737 800
    Copa Airlines (CM 474)Boeing 737 800
  • Copa Airlines (CM 129)
    • M
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    • T
    • -
    • -
    • -
  • 14:40 SDQ
    03:24 SCL
    11Hrs, 44m 1 Stop (PTY)
  • SDQSanto Domingo Las Americas Airport 14:40 - SCL 03:24 11h 44m 1 Stop (PTY) Panama City
  • SDQSanto Domingo Las Americas Airport 14:40
    PTYPanama City Tocumen International Airport 18:51
  • PTYPanama City Tocumen International Airport 16:17
    SCLSantiago Arturo Merino Benitez Airport 03:24
  • 11h 44m (2h 34m)
  • 1 Stop PTY · Panama City 2h 34m
  • Copa Airlines (CM 299)Boeing 737 700
    Copa Airlines (CM 172)Boeing 737 800
  • Copa Airlines (CM 299)
    • -
    • -
    • -
    • -
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    • -
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  • 14:40 SDQ
    03:47 SCL
    12Hrs, 07m 1 Stop (PTY)
  • SDQSanto Domingo Las Americas Airport 14:40 - SCL 03:47 12h 07m 1 Stop (PTY) Panama City
  • SDQSanto Domingo Las Americas Airport 14:40
    PTYPanama City Tocumen International Airport 19:14
  • PTYPanama City Tocumen International Airport 16:17
    SCLSantiago Arturo Merino Benitez Airport 03:47
  • 12h 07m (2h 57m)
  • 1 Stop PTY · Panama City 2h 57m
  • Copa Airlines (CM 299)Boeing 737 700
    Copa Airlines (CM 474)Boeing 737 800
  • Copa Airlines (CM 299)
    • M
    • -
    • -
    • -
    • -
    • S
    • S
  • 14:40 SDQ
    03:47 SCL
    12Hrs, 07m 1 Stop (PTY)
  • SDQSanto Domingo Las Americas Airport 14:40 - SCL 03:47 12h 07m 1 Stop (PTY) Panama City
  • SDQSanto Domingo Las Americas Airport 14:40
    PTYPanama City Tocumen International Airport 19:14
  • PTYPanama City Tocumen International Airport 16:17
    SCLSantiago Arturo Merino Benitez Airport 03:47
  • 12h 07m (2h 57m)
  • 1 Stop PTY · Panama City 2h 57m
  • Copa Airlines (CM 299)Boeing 737 800
    Copa Airlines (CM 474)Boeing 737 800
  • Copa Airlines (CM 299)
    • -
    • -
    • -
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    • -
    • -
    • -
  • 14:40 SDQ
    06:01 SCL
    14Hrs, 21m 1 Stop (PTY)
  • SDQSanto Domingo Las Americas Airport 14:40 - SCL 06:01 14h 21m 1 Stop (PTY) Panama City
  • SDQSanto Domingo Las Americas Airport 14:40
    PTYPanama City Tocumen International Airport 21:28
  • PTYPanama City Tocumen International Airport 16:17
    SCLSantiago Arturo Merino Benitez Airport 06:01
  • 14h 21m (5h 11m)
  • 1 Stop PTY · Panama City 5h 11m
  • Copa Airlines (CM 299)Boeing 737 700
    Copa Airlines (CM 277)Boeing 737 Max 9 Passenger
  • Copa Airlines (CM 299)
    • M
    • -
    • -
    • -
    • F
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    • -
  • 14:40 SDQ
    06:01 SCL
    14Hrs, 21m 1 Stop (PTY)
  • SDQSanto Domingo Las Americas Airport 14:40 - SCL 06:01 14h 21m 1 Stop (PTY) Panama City
  • SDQSanto Domingo Las Americas Airport 14:40
    PTYPanama City Tocumen International Airport 21:28
  • PTYPanama City Tocumen International Airport 16:17
    SCLSantiago Arturo Merino Benitez Airport 06:01
  • 14h 21m (5h 11m)
  • 1 Stop PTY · Panama City 5h 11m
  • Copa Airlines (CM 299)Boeing 737 800
    Copa Airlines (CM 277)Boeing 737 Max 9 Passenger
  • Copa Airlines (CM 299)
    • -
    • -
    • -
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    • -
    • -
    • -
  • 17:10 SDQ
    09:05 SCL
    14Hrs, 55m 1 Stop (MIA)
  • SDQSanto Domingo Las Americas Airport 17:10 - SCL 09:05 14h 55m 1 Stop (MIA) Miami
  • SDQSanto Domingo Las Americas Airport 17:10
    MIAMiami International Airport 22:45
  • MIAMiami International Airport 18:45
    SCLSantiago Arturo Merino Benitez Airport 09:05
  • 14h 55m (4h)
  • 1 Stop MIA · Miami 4h
  • American Airlines (AA 1154)Boeing 737 800
    American Airlines (AA 957)Boeing 777 200
  • American Airlines (AA 1154)
    • M
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    • S
  • 18:15 SDQ
    05:10 SCL
    9Hrs, 55m 1 Stop (BOG)
  • SDQSanto Domingo Las Americas Airport 18:15 - SCL 05:10 9h 55m 1 Stop (BOG) Bogota
  • SDQSanto Domingo Las Americas Airport 18:15
    BOGBogota Airport 21:30
  • BOGBogota Airport 19:50
    SCLSantiago Arturo Merino Benitez Airport 05:10
  • 9h 55m (1h 40m)
  • 1 Stop BOG · Bogota 1h 40m
  • Avianca (AV 251)Airbus
    Avianca (AV 97)Boeing 787 8
  • Avianca (AV 251)
    • -
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    • T
    • F
    • S
    • S
  • 18:38 SDQ
    06:01 SCL
    10Hrs, 23m 1 Stop (PTY)
  • SDQSanto Domingo Las Americas Airport 18:38 - SCL 06:01 10h 23m 1 Stop (PTY) Panama City
  • SDQSanto Domingo Las Americas Airport 18:38
    PTYPanama City Tocumen International Airport 21:28
  • PTYPanama City Tocumen International Airport 20:15
    SCLSantiago Arturo Merino Benitez Airport 06:01
  • 10h 23m (1h 13m)
  • 1 Stop PTY · Panama City 1h 13m
  • Copa Airlines (CM 464)Boeing 737 800
    Copa Airlines (CM 277)Boeing 737 Max 9 Passenger
  • Copa Airlines (CM 464)
    • -
    • T
    • W
    • T
    • F
    • -
    • S
  • 18:38 SDQ
    06:01 SCL
    10Hrs, 23m 1 Stop (PTY)
  • SDQSanto Domingo Las Americas Airport 18:38 - SCL 06:01 10h 23m 1 Stop (PTY) Panama City
  • SDQSanto Domingo Las Americas Airport 18:38
    PTYPanama City Tocumen International Airport 21:28
  • PTYPanama City Tocumen International Airport 20:15
    SCLSantiago Arturo Merino Benitez Airport 06:01
  • 10h 23m (1h 13m)
  • 1 Stop PTY · Panama City 1h 13m
  • Copa Airlines (CM 464)Boeing 737 700
    Copa Airlines (CM 277)Boeing 737 Max 9 Passenger
  • Copa Airlines (CM 464)
    • M
    • -
    • -
    • -
    • -
    • S
    • -
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What’s the most popular airline flying from Santo Domingo to Santiago?

The most popular airline flying from Santo Domingo to Santiago is Copa Airlines. Find the latest flight deals on Wego.

How far is Santiago from Santo Domingo?

The flight distance between Santo Domingo and Santiago is 5775km. Check all available flights on Wego.

When is the earliest and latest flight of the day?

The earliest flight of the day departs at 06:23. The last flight of the day departs at 06:23. See the full list of flight times on Wego.